简体中文

Home / RESEARCH / News RESEARCH

Transplantation of chemically induced pluripotent stem-cell-derived islets under abdominal anterior rectus sheath in a type 1 diabetes patient

Functional profiling of serine, threonine and tyrosine sites

m6A-modified cenRNA stabilizes CENPA to ensure centromere integrity in cancer cells

Proteasome resides in and dismantles plant heat stress granules constitutively

Structural insights into the high-affinity IgE receptor FcεRI complex

Tumor editing suppresses innate and adaptive anti-tumor immunity and is reversed by inhibiting DNA methylation

DNA polymerase δ subunit Pol32 binds histone H3-H4 and couples nucleosome assembly with Okazaki fragment processing

Large-scale calcium imaging reveals a systematic V4 map for encoding natural scenes

Programmable DNA pyrimidine base editing via engineered uracil-DNA glycosylase

A replisome-associated histone H3-H4 chaperone required for epigenetic inheritance

Lysine L-lactylation is the dominant lactylation isomer induced by glycolysis

A transient transcriptional activation governs unpolarized-to-polarized morphogenesis during embryo implantation

Metropolitan pressures: Significant biodiversity declines and strong filtering of functional traits in fish assemblages

Distinct multitrophic biodiversity composition and community organization in a freshwater lake and a hypersaline lake on the Tibetan Plateau

An octopamine-specific GRAB sensor reveals a monoamine relay circuitry that boosts aversive learning

Structural insights into VAChT neurotransmitter recognition and inhibition

Increased transcriptional elongation and RNA stability of GPCR ligand binding genes unveiled via RNA polymerase II degradation

Structure and topography of the synaptic V-ATPase–synaptophysin complex

Capturing totipotency in human cells through spliceosomal repression

Germline Cas9 promoters with improved performance for homing gene drive